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Wavelet Analysis of Biomedical Time Series for Characterization of Blood Circulation Patterns and Human Health Status

Excerpt

Photo-plethysmography (PPG) is frequently used in research on microcirculation of blood. It is a non-invasive procedure and takes minimal time to be carried out. Usually PPG time series are analyzed by conventional linear methods, mainly Fourier analysis. These methods may not be optimal for the investigation of nonlinear effects of the hearth circulation system like vasomotion, autoregulation, thermoregulation, breathing and vessels. The wavelet analysis of the PPG time series is a specific, sensitive nonlinear method for the in vivo identification of hearth circulation patterns and human health status. This nonlinear analysis of PPG signals provides additional information which cannot be detected using conventional approaches. The wavelet analysis has been used to study healthy subjects and to characterize the health status of patients with a functional cutaneous microangiopathy which was associated with diabetic neuropathy. The non-invasive in vivo method is based on the radiation of monochromatic light through an area of skin on the finger. A Photometrical Measurement Device PMD has been developed. The PMD is suitable for non-invasive continuous on-line monitoring of one or more biologic constituent values and blood circulation patterns.

  • Abstract
  • Introduction
  • Materials and Methods
  • Application and Results
  • Conclusions
  • Nomenclature
  • References

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