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Journal Articles

Artificial Neural Network-Aided Computational Approach for Mechanophenotyping of Biological Cells Using Atomic Force Microscopy

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Yuvaraj Kamble, Abhishek Raj, Atul Thakur
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2023, 145(7): 071007.
Paper No: BIO-22-1218
https://doi.org/10.1115/1.4056916
Published Online: April 8, 2023
View Articletitled, Artificial Neural Network-Aided Computational Approach for Mechanophenotyping of Biological Cells Using Atomic Force Microscopy
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Topics: Artificial neural networks, Atomic force microscopy, Simulation, Nanoindentation, Engineering simulation, Platelets, Finite element methods, Finite element model, Testing
Includes: Supplementary data
Journal Articles

Atomic Force Microscopy Stiffness Mapping in Human Aortic Smooth Muscle Cells

Open Access
Claudie Petit, Ali-Akbar Karkhaneh Yousefi, Marine Guilbot, Vincent Barnier, Stéphane Avril
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081001.
Paper No: BIO-21-1065
https://doi.org/10.1115/1.4053657
Published Online: February 21, 2022
View Articletitled, Atomic Force Microscopy Stiffness Mapping in Human Aortic Smooth Muscle Cells
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Topics: Atomic force microscopy, Stiffness, Surface mount components, Muscle
Includes: Supplementary data
Journal Articles

Nonlinear Elastic and Inelastic Properties of Cells

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Wonyeong Jung, Jing Li, Ovijit Chaudhuri, Taeyoon Kim
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. October 2020, 142(10): 100806.
Paper No: BIO-19-1549
https://doi.org/10.1115/1.4046863
Published Online: August 31, 2020
View Articletitled, Nonlinear Elastic and Inelastic Properties of Cells
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Topics: Atomic force microscopy, Computer simulation, Deformation, Mechanical properties, Rheology, Stress, Viscoelasticity, Relaxation (Physics), Fibroblasts, Membranes
Journal Articles

Arterial Stiffness: Different Metrics, Different Meanings

Open Access
B. Spronck, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2019, 141(9): 091004.
Paper No: BIO-19-1040
https://doi.org/10.1115/1.4043486
Published Online: August 2, 2019
View Articletitled, Arterial Stiffness: Different Metrics, Different Meanings
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Topics: Atomic force microscopy, Stiffness, Stress, Pressure, Elasticity, Waves, Deformation, Testing
Journal Articles

Atomic Force Microscopy of Phase Separation on Ruptured, Giant Unilamellar Vesicles, and a Mechanical Pathway for the Co-Existence of Lipid Gel Phases

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Yanfei Jiang, Kenneth M. Pryse, Srikanth Singamaneni, Guy M. Genin, Elliot L. Elson
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2019, 141(7): 071003.
Paper No: BIO-18-1528
https://doi.org/10.1115/1.4043871
Published Online: June 13, 2019
View Articletitled, Atomic Force Microscopy of Phase Separation on Ruptured, Giant Unilamellar Vesicles, and a Mechanical Pathway for the Co-Existence of Lipid Gel Phases
Open the PDF for Atomic Force Microscopy of Phase Separation on Ruptured, Giant Unilamellar Vesicles, and a Mechanical Pathway for the Co-Existence of Lipid Gel Phases in another window
Topics: Atomic force microscopy, Fluorescence, Membranes, Phase separation, Microscopy
Journal Articles

Cholesterol-Dependent Modulation of Stem Cell Biomechanics: Application to Adipogenesis

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Shan Sun, Djanybek Adyshev, Steven Dudek, Amit Paul, Andrew McColloch, Michael Cho
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2019, 141(8): 081005.
Paper No: BIO-18-1375
https://doi.org/10.1115/1.4043253
Published Online: May 6, 2019
View Articletitled, Cholesterol-Dependent Modulation of Stem Cell Biomechanics: Application to Adipogenesis
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Topics: Atomic force microscopy, Biomechanics, Membranes, Proteins, Stem cells, Cellular mechanics, Stiffness, Elasticity
Journal Articles

A Finite Element Bendo-Tensegrity Model of Eukaryotic Cell

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Yogesh Deepak Bansod, Takeo Matsumoto, Kazuaki Nagayama, Jiri Bursa
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2018, 140(10): 101001.
Paper No: BIO-16-1380
https://doi.org/10.1115/1.4040246
Published Online: June 21, 2018
View Articletitled, A Finite Element Bendo-Tensegrity Model of Eukaryotic Cell
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Topics: Cellular mechanics, Deformation, Finite element analysis, Materials properties, Simulation, Stiffness, Stress, Tensegrity, Antilock braking systems, Elongation
Journal Articles

Effect of Osmotic Pressure on Cellular Stiffness as Evaluated Through Force Mapping Measurements

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Hsien-Shun Liao, Peter J. Wen, Ling-Gang Wu, Albert J. Jin
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. May 2018, 140(5): 054502.
Paper No: BIO-17-1381
https://doi.org/10.1115/1.4039378
Published Online: March 16, 2018
View Articletitled, Effect of Osmotic Pressure on Cellular Stiffness as Evaluated Through Force Mapping Measurements
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Topics: Atomic force microscopy, Cell membranes, Force measurement, Pressure, Stiffness, Young's modulus, Compression, Cellular mechanics
Journal Articles

Multiscale Poroviscoelastic Compressive Properties of Mouse Supraspinatus Tendons Are Altered in Young and Aged Mice

Open Access
Brianne K. Connizzo, Alan J. Grodzinsky
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2018, 140(5): 051002.
Paper No: BIO-17-1343
https://doi.org/10.1115/1.4038745
Published Online: February 15, 2018
View Articletitled, Multiscale Poroviscoelastic Compressive Properties of Mouse Supraspinatus Tendons Are Altered in Young and Aged Mice
Open the PDF for Multiscale Poroviscoelastic Compressive Properties of Mouse Supraspinatus Tendons Are Altered in Young and Aged Mice in another window
Topics: Tendons, Compression, Testing, Atomic force microscopy, Rheology, Fluid dynamics
Journal Articles

Simultaneous Analysis of Elastic and Nonspecific Adhesive Properties of Thin Sample and Biological Cell Considering Bottom Substrate Effect

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Vishwanath Managuli, Sitikantha Roy
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2017, 139(9): 091008.
Paper No: BIO-16-1334
https://doi.org/10.1115/1.4037289
Published Online: July 28, 2017
View Articletitled, Simultaneous Analysis of Elastic and Nonspecific Adhesive Properties of Thin Sample and Biological Cell Considering Bottom Substrate Effect
Open the PDF for Simultaneous Analysis of Elastic and Nonspecific Adhesive Properties of Thin Sample and Biological Cell Considering Bottom Substrate Effect in another window
Topics: Adhesion, Adhesives, Atomic force microscopy, Biological cells, Pressure, Stiffness, Biomechanics, Materials properties
Journal Articles

A Validation Study of the Repeatability and Accuracy of Atomic Force Microscopy Indentation Using Polyacrylamide Gels and Colloidal Probes

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Donghee Lee, Sangjin Ryu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. April 2017, 139(4): 044502.
Paper No: BIO-16-1282
https://doi.org/10.1115/1.4035536
Published Online: February 14, 2017
View Articletitled, A Validation Study of the Repeatability and Accuracy of Atomic Force Microscopy Indentation Using Polyacrylamide Gels and Colloidal Probes
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Topics: Atomic force microscopy, Probes, Microscopy, Elasticity
Includes: Supplementary data
Journal Articles

Study of Cholesterol Repletion Effect on Nanomechanical Properties of Human Umbilical Vein Endothelial Cell Via Rapid Broadband Atomic Force Microscopy

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Bo Yan, Juan Ren, Yue Liu, Huarong Huang, Xi Zheng, Qingze Zou
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. March 2017, 139(3): 034501.
Paper No: BIO-15-1627
https://doi.org/10.1115/1.4035260
Published Online: January 23, 2017
View Articletitled, Study of Cholesterol Repletion Effect on Nanomechanical Properties of Human Umbilical Vein Endothelial Cell Via Rapid Broadband Atomic Force Microscopy
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Topics: Atomic force microscopy, Endothelial cells, Excitation, Young's modulus, Oscillations, Cell membranes, Elasticity, Viscoelasticity, Mechanical properties
Journal Articles

Mechanical Characterization of a Dynamic and Tunable Methacrylated Hyaluronic Acid Hydrogel

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Matthew G. Ondeck, Adam J. Engler
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2016, 138(2): 021003.
Paper No: BIO-15-1566
https://doi.org/10.1115/1.4032429
Published Online: January 27, 2016
View Articletitled, Mechanical Characterization of a Dynamic and Tunable Methacrylated Hyaluronic Acid Hydrogel
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Topics: Hydrogels, Stiffness, Ultraviolet radiation, Fibroblasts, Polymers, Polymerization, Atomic force microscopy
Includes: Supplementary data
Journal Articles

A Quantitative Interpretation of the Response of Articular Cartilage to Atomic Force Microscopy-Based Dynamic Nanoindentation Tests

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Matteo Taffetani, Roberto Raiteri, Riccardo Gottardi, Dario Gastaldi, Pasquale Vena
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2015, 137(7): 071005.
Paper No: BIO-14-1615
https://doi.org/10.1115/1.4030175
Published Online: July 1, 2015
View Articletitled, A Quantitative Interpretation of the Response of Articular Cartilage to Atomic Force Microscopy-Based Dynamic Nanoindentation Tests
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Topics: Anisotropy, Atomic force microscopy, Biological tissues, Cartilage, Fundamental forces (Physics), Microscopy, Nanoindentation, Permeability, Phase shift, Constitutive equations
Journal Articles

Biophysical Analysis of Dystrophic and Osteogenic Models of Valvular Calcification

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Joseph Chen, Jon R. Peacock, Janelle Branch, W. David Merryman
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Forum
J Biomech Eng. February 2015, 137(2): 020903.
Paper No: BIO-14-1418
https://doi.org/10.1115/1.4029115
Published Online: February 1, 2015
View Articletitled, Biophysical Analysis of Dystrophic and Osteogenic Models of Valvular Calcification
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Topics: Assaying, Atomic force microscopy, Biomechanics, Valves, X-rays, Bone, Biomaterials, Cellular mechanics, Statistical analysis, Biological tissues
Journal Articles

Determination of Strain-Rate-Dependent Mechanical Behavior of Living and Fixed Osteocytes and Chondrocytes Using Atomic Force Microscopy and Inverse Finite Element Analysis

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Trung Dung Nguyen, YuanTong Gu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2014, 136(10): 101004.
Paper No: BIO-13-1485
https://doi.org/10.1115/1.4028098
Published Online: August 6, 2014
View Articletitled, Determination of Strain-Rate-Dependent Mechanical Behavior of Living and Fixed Osteocytes and Chondrocytes Using Atomic Force Microscopy and Inverse Finite Element Analysis
Open the PDF for Determination of Strain-Rate-Dependent Mechanical Behavior of Living and Fixed Osteocytes and Chondrocytes Using Atomic Force Microscopy and Inverse Finite Element Analysis in another window
Topics: Atomic force microscopy, Chondrocytes, Finite element analysis, Mechanical behavior
Journal Articles

Elasticity of Human Embryonic Stem Cells as Determined by Atomic Force Microscopy

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Robert Kiss, Henry Bock, Steve Pells, Elisabetta Canetta, Ashok K. Adya, Andrew J. Moore, Paul De Sousa, Nicholas A. Willoughby
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2011, 133(10): 101009.
https://doi.org/10.1115/1.4005286
Published Online: November 7, 2011
View Articletitled, Elasticity of Human Embryonic Stem Cells as Determined by Atomic Force Microscopy
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Topics: Atomic force microscopy, Elasticity, Stem cells, Young's modulus, Fibroblasts
Journal Articles

Age-Dependent Regional Mechanical Properties of the Rat Hippocampus and Cortex

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Benjamin S. Elkin, Ashok Ilankovan, Barclay Morrison, III
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. January 2010, 132(1): 011010.
https://doi.org/10.1115/1.4000164
Published Online: December 18, 2009
View Articletitled, Age-Dependent Regional Mechanical Properties of the Rat Hippocampus and Cortex
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Topics: Atomic force microscopy, Biological tissues, Brain, Compression, Elastic moduli, Mechanical properties, Proteins
Journal Articles

Measuring Viscoelasticity of Soft Samples Using Atomic Force Microscopy

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S. Tripathy, E. J. Berger
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. September 2009, 131(9): 094507.
https://doi.org/10.1115/1.3194752
Published Online: August 28, 2009
View Articletitled, Measuring Viscoelasticity of Soft Samples Using Atomic Force Microscopy
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Topics: Agar, Atomic force microscopy, Relaxation (Physics), Viscoelasticity, Polymers
Journal Articles

Role of Cytoskeletal Components in Stress-Relaxation Behavior of Adherent Vascular Smooth Muscle Cells

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Jason D. Hemmer, Jiro Nagatomi, Scott T. Wood, Alexey A. Vertegel, Delphine Dean, Martine LaBerge
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. April 2009, 131(4): 041001.
https://doi.org/10.1115/1.3049860
Published Online: January 20, 2009
View Articletitled, Role of Cytoskeletal Components in Stress-Relaxation Behavior of Adherent Vascular Smooth Muscle Cells
Open the PDF for Role of Cytoskeletal Components in Stress-Relaxation Behavior of Adherent Vascular Smooth Muscle Cells in another window
Topics: Atomic force microscopy, Muscle, Relaxation (Physics), Stress, Viscoelasticity